ABSTRACT
BACKGROUND: The role of Helicobacter pylori in stomach carcinogenesis is currently under study. H pylori-related chronic gastritis leading to dysplasia or intestinal metaplasia (IM) especially of the colonic type is postulated as one of the mechanisms. METHODS: We studied 120 patients with or without H pylori infection to determine the frequency of occurrence of IM in the stomach. RESULTS: IM was found in 16.6% of patients; most cases had the small intestinal type, which is not known to have a malignant potential. There was no relation between H pylori infection and development of IM. CONCLUSION: H pylori infection leading to IM does not appear to be a factor in the genesis of carcinoma stomach in our population.
Subject(s)
Adult , Duodenal Neoplasms/epidemiology , Evaluation Studies as Topic , Female , Gastric Mucosa/pathology , Helicobacter Infections/complications , Helicobacter pylori/isolation & purification , Humans , Incidence , India/epidemiology , Intestinal Mucosa/pathology , Male , Metaplasia , Middle Aged , Precancerous Conditions/pathology , Risk Factors , Stomach Neoplasms/epidemiologyABSTRACT
Balloon dilation is an effective modality of treatment for esophageal strictures. As standard through-the-scope balloons do not pass through the biopsy channel of pediatric endoscopes, we have developed a technique by which these balloons can be used in pediatric patients by passing them alongside the endoscope. We report our experience of dilation in four patients using this technique.
Subject(s)
/instrumentation , Child , Esophageal Stenosis/therapy , Esophagoscopes , Female , Humans , Infant , MaleABSTRACT
Twenty five patients with pemphigus vulgaris were prospectively studied for esophageal involvement by endoscopic examination. Eighteen (72%) had esophageal involvement; the majority of the lesions were bullae. Histological examination showed acantholysis of the cells and exuberant inflammation.
Subject(s)
Acantholysis/pathology , Esophagoscopy , Esophagus/pathology , Female , Humans , Male , Pemphigus/pathology , Prospective StudiesABSTRACT
Multiple esophageal webs are rare and are described in association with gastroesophageal reflux disease (GERD). We describe a case of multiple esophageal webs secondary to GERD.
Subject(s)
Aged , Esophageal Diseases/etiology , Gastroesophageal Reflux/complications , Humans , MaleABSTRACT
Rectal involvement in lymphogranuloma venereum (LGV) is more common in women. Inguinal bubo is often absent and the patient seeks medical attention only at a late stage when rectal stricture has developed. LGV rectal stricture resembles and is known to predispose to rectal cancer. Hence it is necessary to rule out rectal malignancy in patients with LGV stricture. We report a case of rectal LGV associated with rectal adenocarcinoma.